I reach out to comfort him but stop myself - a light touch can set Jacob off. He doesn’t like handshakes or pats on the back or someone ruffling his hair. “Jacob,” I begin, and then I realize that he isn’t sulking at all. He holds up the telephone receiver he’s been hunched over, so that I can see the smudge of black on the side. “You missed a fingerprint too,” Jacob says cheerfully. “No offense, but you would make a lousy crime scene investigator.” He rips off a sheet of paper towel off the roll; dampens it in the sink. “Don’t worry, I’ll clean up all the blood.”
PD was first formally described in 1817,  however L-dopa did not enter clinical practice until almost 1970.   In these initial works there were already reports of neuropsychiatric complications.  During the following decades cases featuring DDS symptoms in relation to dopamine therapy such as hypersexuality, gambling or punding , appeared.    DDS was first described as a syndrome in the year 2000.  Three years later the first review articles on the syndrome were written, showing an increasing awareness of the DDS importance.    Diagnostic criteria were proposed in 2005. 
Each ministry operates slightly differently, but the basic premise remains the same: Every month, members pay a certain amount (their “share”) into the ministry. When a need arises — say you break your leg, or get diagnosed with lung cancer, or have a baby — you submit your bills to the ministry’s office and you receive payments for the total amount you owe, usually in the form of checks or direct deposits from various members. Some ministries hold the funds in an online escrow account; others have members mail their checks directly to the other members. Shares out are published by the ministries each month, so you can see that your $405 is going to, say, Irene in Idaho who recently had a hip replacement.