The Mackinac Center for Public Policy (Vedder 1999) employed a wage differential approach to calculate costs of prevailing wages on Michigan government construction. The author used a sample of wages paid in the Detroit area suburbs to calculate a 40% diff
erence between market and prevailing rates, a premium that would, hypothetically, drive up construction costs in Michigan by 10%. 9 Applying this 10% to state construction costs and non-construction capital outlays resulted in an estimate of $275 million in additional costs due to state prevailing wages.
“The microbiome is a component intertwined in a complex puzzle,” Relman continues. “And sometimes the genetics is so strong that it will override and drive back the microbiota.” Genetic variations might explain why only four of the seven saccharin-fed humans had a change in their gut bacteria, for instance, although genetics is only one of a number of possible factors. And if someone is genetically predisposed to obesity and consumes a diet that promotes that obesity, the microbes might change to take advantage of that diet, thereby amplifying the effect.